What to Know About Type 1 Diabetes Mellitus - Essay Sample

Introduction

Type 1 diabetes is described by the decimation of the pancreatic beta cells. Insulin is produced by the pancreatic beta cells. Destruction of these cells results in the non-production of Insulin, as witnessed in type 1 diabetes mellitus (Katsarou et al., 2017). The patient will, therefore, need insulin shots to be able to utilize glucose from consumed food.

Is your time best spent reading someone else’s essay? Get a 100% original essay FROM A CERTIFIED WRITER!

Order now

What is Long-Acting Insulin?

This insulin furnishes a consistent basal insulin profile with negligible peak action and is injected subcutaneously once every day. The beginning of activity is inside two hours, and they have a more drawn out length of activity of up to twenty-four hours or more.

How to Administer Long-Acting Insulin

This Insulin is administered as a shot subcutaneously, can be injected on upper arms, thighs, or abdomen, and should be used consistently simultaneously (Katsarou et al., 2017). Rotate where you make the shot inside your chosen site. Your primary care physician will let you know the dosage and how often you should inject Insulin. It comes in vials or pens. If you miss a dose, take it when you can. If it is over six hours past your dosage-time, call your diabetes care provider, and, take two dosages at the same time to compensate for a missed dose. Never mix different types of Insulin in the same syringe.

Possible Side Effects

Itching at the injection site, pain, redness, swelling, burning sensation, and lump formation may be present in some patients. It is very important to rotate the injection spot every time Insulin is administered (Laranjeira et al., 2018).

Adverse Effects

Hypersensitivity symptoms have included both localized and general systemic responses. Hypersensitivity is rare though it can occur in some individuals. These can present as local reactions such as erythema, edema, pruritus at the injection site, or more life-threatening, generalized systemic anaphylaxis (Laranjeira et al., 2018). Most minor responses to Insulin at the injection site resolve in a couple of days to half a month.

Available Long-Acting Insulin and Storage

Opened Insulin should be stored at room temperature while protecting Insulin from direct sunlight and heat. Store unopened Insulin in the fridge and try not to freeze it. It is very ethical to keep medication out of the range of children also, pets alike.

Long-acting insulin Viability at room temperature Onset of action Duration of action

Lantus U-100 28 days 1-2 hours 24 hours

Toujeno U-300 42 days 6 hours 24-36 hours

Levemir Detemir 42 days 1-2 hours 24 hours

Basaglar U-100 28 days 1-2 hours 24 hours

Tresiba U-200 56 days 1-4 hours 42 hours

When to Consult a Diabetic Healthcare Provider

Regular high and low blood sugar

Feeling debilitated, nausea and spewing

Flu-like side effects for example, any indication of a hypersensitive response, hives or pruritus, difficulty in breathing or wheezing, facial edema, and peripheral edema.

What to Know While On Insulin Therapy

Before taking this medication, inform your primary physician about other medications you are currently taking, including OTC meds and herbal medicines, presence of Liver or Kidney disease. There is a need to share about pregnancy and plans for pregnancy and breastfeeding. Continuously carry some starch as this will help avoid blood sugar going low. Your insulin dose may need to change when you are sick or at the point when you change your eating regimen or activity. Alcohol intake may cause indications that vibe like low blood glucose. Check your blood glucose regularly when drinking liquor. Do not change brands of Insulin without consulting your primary care physician.

References

Katsarou, A., Gudbjörnsdottir, S., Rawshani, A., Dabelea, D., Bonifacio, E., Anderson, B. J., & Lernmark, Å. (2017). Type 1 diabetes mellitus. Nature reviews Disease primers, 3(1), 1-17. https://www.nature.com/articles/nrdp201716

Laranjeira, F. O., de Andrade, K. R., Figueiredo, A. C., Silva, E. N., & Pereira, M. G. (2018). Long-acting insulin analogues for type 1 diabetes: An overview of systematic reviews and meta-analysis of randomized controlled trials. PloS one, 13(4), e0194801. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194801