Definition of LincRNA
Long intergenic non-coding RNA has been selected for this specific assignment. LincRNA is defined as a type of non-coding RNA that have more than 200 nucleotides and do not overlap glossed coding genes.
Role of LincRNA
LincRNA plays a critical role in the regulation of biological processes . In addition to that it makes about a half of human transcripts 
Classification and structure of LincRNA
The LincRNA falls in the category of noncoding RNAs. It also shows a vital part in cell differentiation, cell propagation, and remodeling of chromatin by trans and cis mechanism through the use of proteins that are scaffolded . Furthermore, it regulates the adjacent genes as well as taking part in the production of neuropeptides . It is discovered that through the structural elements, lincRNA interacts with nucleic acids through sequence complimentary .
Altering LincRNA with cancer types
The Long intergenic non-coding RNA remodels architecture of the genome . It has also been altered in more than two cancer types whereby the nature of technology applied in the experiment was on public RNA sequence datasets of the four common solid cancers. 
Concept of LincRNA
Most of the lincRNAs have been identified of having no relationship with tumors. The realization was after investigating their functions by using a database. . LincRNAs are identified with the capability of inhibiting the moment when they are undergoing sequestration. For example, the lincRNA has been identified to form a double-stranded structure that binds DNA. This is vital as it blocked receptors from target genes as well as their transcription through promoting stem cell multiplication as well as formation of nuclear which in turn has affected expressions of genes. From annotated lincRNAs, two polypeptides are obtained to regulate membrane pump that in turn controls relation of the muscle .
Characteristics of LincRNA
It is evident that LincRNAs are involved in the embryonic development. In addition to that lincRNA was identified to be having the lower expression by the approach of comparing them to PCGs. 
The research has shown that genomic mutations within cancer resides deep inside in the regions that do not convert proteins . Those regions are usually transcribed into lincRNA 
Functions of Alternative splicing
Notably, the action of splicing takes place through the concerted activities of multi-subunit complexes . Cancer is also a type of disease that is characterized by a variety of epigenetics and genetic aberrations. . It has been noted that the fundamental role of alternative splicing is to promote sustained proliferation signals in cancer. 
Causes of alternative splicing
The defects in the alternative splicing is mostly found in the human tumors and it results from mutations in splicing regulatory elements of particular kind of cancer 
Functions of LincRNA
RNA splicing regulators has seen to emerge as a fresh class of oncoproteins as well as tumors suppressors . It has also contributed to the progression of disease through RNA isoforms modulation that are involved in seal cancer pathways .
Importance of LincRNA
The Polyadenylation status illustrates that LincRNAs have been identified to be vital controllers for transcription, epigenetic inflection as well as transformation. 
Other Functions of LincRNA
Some of the other functions of long intergenic non-coding RNA includes the development of stem cells as the key regulators in various cellular processes as well as binding and modulation of stability and translation of other RNAs .
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